The Best Weed Killers for Your Garden and How to use Weed Killers Successfully may earn a small commission (at no extra cost to the user) from Amazon and other online retailers if a purchase is made after clicking a link. I appreciate your continuing support.

So many times we hear the question. What are the best weed killers for your garden and how do I use them effectively? 

Most of us find weeds a complete garden bore. Perfect gardens are not made of them. Below we have listed the best weed killers on the market and how to use them.

There are two basic groups, perennial weeds and annual weeds.

So how can you tell the difference and more importantly get rid of them once and for all.

Simply put, perennial weeds and annual weeds are defined by their roots and how they propagate themselves.  Is the weed easy to pull out of the ground? If so, it is probably an annual. “Herb Robert” is a good example of this. Its roots are shallow in the soil, generally quite small and weak. One sharp tug and the whole thing is out.

If the roots are quite thick and go deeper (3 to 4 inches or more) it is probably a perennial. The dreaded Ground Elder is a good example of this. With a very complex white root system, they wind their way through your lovely soil.

So, how do we get rid of the weeds?

Perennial weeds that have a strong root system are mainly propagated by seed. They can also propagate themselves by their roots. This makes them difficult to kill. For these hard to kill weeds a SYSTEMIC weed killer is best. Whilst they may take longer to work (sometimes 4 weeks) they kill the weed from the root all the way to the leaves which is essential.

Annual weeds grow from a seed, flower and then die. The flower heads distribute the seeds over the soil and the whole process starts again. For these weeds, a different method needs to be employed. CONTACT weed killer is the best course of action in our experience. These contact weed killers effectively burn the leaves of the weed within a few days, cutting off its food supply of light. The weeds shrivel up and are then not able to produce a flower or set seed. They then die, breaking the cycle.

The Best Weed Killer 

Back in 2016, we started using a new weed killer from Neudorff which contains a pelargonic acid (An organic compound found naturally in plants). We were very impressed. It is incredibly fast acting and effective (visible results within 1 hour, see the pics below) on general perennial and annual weeds. It is one of the fastest, effective weed killers we have seen.


It’s 2020 and with the wet spring this year, we are inundated with weeds. I thought you would like to know we are still using the Neudorff weed killer. We found the weeds died successfully with the first application so there was no need to buy more weed killer to give the weeds a second dose.

Some good news, we have discovered that Neudorff Weed killer also kills moss, very successfully. The company produces two products, a weedkiller and a moss and algae killer.

The only difference is that the weedkiller contains a growth retardant that stops the weeds sprouting and so is slightly more expensive. This is the best weed and moss killer for block paving or tarmac drives.

You can see the speed at which the weedkiller works in the pictures below. Taken at a slightly different angle so that the sun was behind me.

In less than 4 hours the weeds are nearly gone. 

Why are my weeds not dying?

In our experience, the majority of weed killers work. The lack of success is down to one or more reasons.

  • Poor coverage of the leaves
  • Incorrect mixing
  • Expectations of the weed killer i.e. are you using contact weed killers on perennial weeds?
  • Rainfall after application. Washing the chemical from the leaves

Tough weeds

Be patient with strong growing perennials like bindweed, bramble and nettles. It is important to allow the chemical to keep acting on the leaves so it can work its way down the plant to the root (systemically). If the leaves wither quickly it stops the systemic action.

Read my Post on Killing Ivy and Brambles

Top Tip

Any weed killer containing a substance called glyphosate will kill weeds down to the roots. Look on the label for a section that quotes glyphosate g/l. A weaker solution of Round up from the garden centre might say 190g/l glyphosate. A professional weed killer will contain 360g/l or more.

We have listed two exceptionally strong weedkillers.

  1. Gallup Home and Garden contains 360g/l glyphosate  which will kill everything. The good news is that it is only active on green matter therefore you can replant an area as soon as the weeds have died.
  2. Vitax SBK Brushwood killer. This strong weedkiller will kill woody weeds like brambles, tree saplings, nettles and docks. It is a selective weedkiller which means it won’t kill the grass. So you can use it near your lawn.

You will need to buy a separate sprayer unit when using the very strong weed killers.


Just a word on sprayers. If you have a drive, patio or weedy borders, it does help to have a backpack sprayer.  Although they are initially expensive it is well worth the investment. You won’t have to keep returning to refill and it is a lot easier to constantly pump and spray whilst walking along.

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